autoimmune disease

MS Read-a-Thon in Canada Extended to Meet Goal

The MS Society of Canada‘s virtual MS Read-a-Thon event has been extended to March 20, giving children and families throughout Canada extra time to enjoy reading while raising funds for the multiple sclerosis (MS) community. The event, which began Jan. 27, seeks to generate $110,000 to…

Autoimmune Patients Want Clearer COVID-19 Vaccine Info

Patients with autoimmune diseases, including multiple sclerosis (MS), are uncertain about how to protect themselves against COVID-19, especially with regards to booster shots of the vaccine. According to a national survey by the nonprofit Alliance for Patient Access, these patients are confused due to conflicting information from the…

Tonix Files for Patent for TNX-1500 to Treat Autoimmune Diseases

Tonix Pharmaceuticals has filed a patent application with the World Intellectual Property Organization covering the use of TNX-1500 — its third-generation anti-CD154 antibody — for the prevention and treatment of autoimmune diseases, such as multiple sclerosis (MS), and organ transplant rejection. “There remains a significant need for new treatments with improved…

Finding My Way Through Sickness and Sadness with SPMS

I am hyperaware of the fragility of life. More specifically, the fragility of mine. Secondary progressive multiple sclerosis is an autoimmune disease. My immune system eats away at the myelin sheath surrounding my nerves. My disease-modifying therapy is an immunosuppressant. This further weakens my immunity. I have known…

MS Is a Pain, and Doctors Should Know It

Dear Doctor, Why is it that you, or at least some of your colleagues, think that multiple sclerosis isn’t painful? Did you skip the med school class where they discussed MS? Are you not a neurologist, or are you a neurologist who doesn’t specialize in MS? Whatever the reason, this “MS…

Is There a Connection Between Fibromyalgia and MS?

I’ve often wondered if there may be a connection between fibromyalgia, multiple sclerosis (MS), and other neurological conditions. Back in the early 1990s, my doctor suspected fibromyalgia as the culprit for my fatigue, aches, and pains. At the time, doctors diagnosed fibromyalgia by the use of tender points.

Researchers Develop New Method to Specifically Target Immune Cells that Trigger MS, Other Autoimmune Processes

Researchers at Cincinnati Children’s Hospital Medical Center (CCHMC) have developed a new experimental method to specifically target unwanted activation of the immune system without the toxicity of current immunoregulatory drugs. According to the study “Manipulating DNA damage-response signaling for the treatment of immune-mediated diseases,” published in the journal …

Nektar Therapeutics Starts Phase 1 Trial of NKTR-358 for Autoimmune Diseases

Nektar Therapeutics has started a Phase 1 clinical trial of its biologic therapy NKTR-358 for inflammatory disorders and autoimmune diseases like multiple sclerosis. NKTR-358 is a first-in-class regulatory T-cell stimulator designed to correct the immune system dysfunction associated with these disorders. It targets regulatory T-cells, or Tregs. Other immunosuppressant therapies suppress the…

Making Careful Travel Plans for MS Medications and Supplies

If I were playing “Chronic Disease Bingo,” I’d be a winner! In addition to MS, I have three other chronic health conditions. While that may sound bad, it’s not unusual in the world of autoimmune disease, and I consider myself fairly healthy. This is thanks partly to attitude, but…

‘Master Switch’ for Autoimmune Diseases Like MS Potentially Seen in DNA of Immune Cells

Regions of DNA called super-enhancers regulate immune cell activity, including the body’s response to threats like inflammation or pathogens, and now scientists have found that they also harbor genetic variants associated with autoimmune diseases — gene variants that may be the “master switches” for these conditions. The findings were described in the study “…

Gut Microbiota in Young MS Patients Is Higher in Pro-Inflammatory Bacteria Than Usual, Study Finds

Children and adolescents with multiple sclerosis (MS) differ from others in the composition of their gut flora, with higher levels of inflammation-causing bacteria and lower levels of anti-inflammatory bacteria, according to a study from  the University of British Columbia, Canada. The findings, supporting previous hypotheses that the composition of the gut microbial community could influence the development…

Rise in MS and Autoimmune Disease Linked to Processed Foods

In a new study, researchers found that additives common to processed foods can damage the tight junctions that protect the intestinal mucosa, and which are essential to the intestinal tolerance and immunity balance that works to prevent autoimmune diseases such as multiple sclerosis (MS). The article, titled “Changes in…

Hypoxia-Measuring Technology in MS Could Be Potential Biomarker for Treatment Responses

In a new study entitled “Reduced cortical microvascular oxygenation in multiple sclerosis: a blinded, case-controlled study using a novel quantitative near-infrared spectroscopy method,” a team of researchers at the Hotchkiss Brain Institute, Cumming School of Medicine, University of Calgary investigated whether frequency domain near-infrared spectroscopy technology can measure the potential…

Brain-specific B Cells’ Reactivity Determines Glatiramer Acetate Therapy Success in MS Patients

In a new study entitled “The brain antigen-specific B cell response correlates with glatiramer acetate responsiveness in relapsing-remitting multiple sclerosis patients,” a team of scientists discovered that differences in response to glatiramer acetate therapy among multiple sclerosis (MS) patients is potentially dependent on the presence of reactive brain-specific B…

Nano-Drugs in Liposomes Could Treat Multiple Sclerosis

Nano-drugs encased in liposomes could one day be used to treat neurological diseases like multiple sclerosis (MS), according to a new study published July 6th in the journal, PloS One. A liposome is a small, fat soluble droplet that can contain a water soluble drug. Liposomes might…