depression

Low blood levels of ferritin — the main form of iron stored in cells — are significantly associated with more severe depressive symptoms and poorer quality of life in multiple sclerosis (MS) patients, a small study from Poland reports. Data showed no link between the levels of other measures of…

People with multiple sclerosis (MS) have a higher burden of mental disorders than healthy people or people with rheumatoid arthritis, a French population-based study suggests. The study, “Prevalence of mental disorders is higher in patients with multiple sclerosis than in the general population or in patients with…

While the COVID-19 pandemic had an impact on the psychological well-being of people with progressive forms of multiple sclerosis (MS), it led to minimal changes in depression, anxiety, and quality of life, according to data from an international survey. This was true even for the 4% of patients who reported…

Donepezil — an approved treatment for Alzheimer’s disease — eased cognitive impairment, depression, and improved other quality-of-life measures in multiple sclerosis (MS) patients with mild to moderate disability, according to results of a single-site clinical trial. The study, “Effect of Donepezil on Cognitive Impairment, Quality of Life, and Depression…

Comorbidities such as anxiety and depression are associated with a significantly increased risk of relapse in people with relapsing-remitting multiple sclerosis (RRMS), a clinical trial analysis has found.  Anxiety and abnormal blood lipids (fats) also increased the risk of any RRMS disease activity.  Based on those findings, researchers…

Gilenya May Help Control Severe Respiratory Disease in COVID-19 This story caught my eye, but not because of the possibility that Gilenya may help someone recover from COVID-19. It caught my eye because this information may give false hope to some people. Some doctors think that at a…

A likelihood of depression is two to three times higher in multiple sclerosis (MS) patients in the U.S. and U.K. than in similar groups of people in these countries without the disease, a study reported. This risk was also “most evident in the first five years after MS diagnosis” among…

In this column, I’ll be highlighting some of the research presented at this year’s Americas Committee for Treatment and Research in Multiple Sclerosis (ACTRIMS) Forum, held last week in West Palm Beach, Florida. #ACTRIMS2020 — Remyelination in Adult Animal Brains Possible via Cell Transplant, Study Says You’ll need…

Multiple sclerosis (MS) patients with depression are more likely to have worsening neurological function compared with those who do not have the mood disorder, results from a real-world study show. The findings were presented Feb. 27 by Jenny Feng, MD, in an oral presentation — titled “…

The likelihood of discontinuing treatment with Tysabri (natalizumab) is higher among patients with progressive relapsing multiple sclerosis, and those who smoke and are depressed, a study reported. Progressive relapsing MS (PRMS) is now largely considered a subset of primary progressive MS, or PPMS marked by periods…

I am hyperaware of the fragility of life. More specifically, the fragility of mine. Secondary progressive multiple sclerosis is an autoimmune disease. My immune system eats away at the myelin sheath surrounding my nerves. My disease-modifying therapy is an immunosuppressant. This further weakens my immunity. I have known…

A psychologist at Swinburne University of Technology in Melbourne has been awarded an incubator grant by MS Research Australia to identify ways to better detect and treat depression in people with multiple sclerosis (MS). The grant given to Lisa Grech, PhD, with the School of Health Sciences at Swinburne, is…

Trials testing new immunotherapies for multiple sclerosis (MS) should focus more on patients’ experiences and on symptoms relevant for them such as fatigue, depression, and cognitive difficulties, a German working group recommends. According to the team, which is working on developing new standards for planning MS trials, clinical…

Effective money management, critical to independent living, is particularly  difficult for people whose multiple sclerosis (MS) affects executive thinking skills and who struggle with depression and anxiety, a study reports. The study, “Money Management in Multiple Sclerosis: The Role of Cognitive, Motor, and Affective Factors,” was published in the…

Pear Therapeutics announced that a first patient is being treated in Part 2 of its feasibility trial of Pear-006, a software application that, given along with a disease-modifying therapy, delivers cognitive behavioral therapy and other neurobehavioral approaches to ease depression in people with multiple sclerosis (MS). Pear-006, being developed…

CHMP Favors Mayzent as Oral Treatment Specifically for Active SPMS Patients in EU Mayzent (siponimod) is one of the newest disease-modifying treatments (DMT). I’m pleased that the Committee for Medicinal Products of Human Use (CHMP), which reviews treatments in the European Union, has recommended that the DMT be approved…

Three academic research institutions launched the Weill Neurohub initiative, an effort to speed the discovery and development of therapies for neurological diseases that include multiple sclerosis (MS), Parkinson’s and Alzheimer’s disease, and for psychiatric disorders like anxiety, depression, and schizophrenia. The initiative unites three West Coast…

Depression and fatigue have a more powerful influence on the overall health-related quality of life, compared to physical impairment, among patients with multiple sclerosis, a new study shows. The study, “Contributing factors to health‐related quality of life in multiple sclerosis,” was published in the journal Brain and…

Multiple sclerosis (MS) patients in the U.S. are three times more likely to have mental or behavioral health issues, including depression and substance abuse (substance use disorder), than the general population, a report based on commercial insurance claims by the Blue Cross Blue Shield Association (BCBSA) found. All…

Sanofi is working with Happify Health to develop an app that addresses the mental health of people with multiple sclerosis (MS) through cognitive behavior therapy. The physical symptoms of MS, such as fatigue and spasticity, are well-documented. But many patients also struggle with bouts of depression,…

Feeling tired, depressed, or anxious? Maybe it has to do with your social cognition. Social cognition involves empathy and recognizing the emotions that are revealed by someone’s facial expression. That expression may show fear or disgust. Or it may warn us of danger. Social cognition also involves the…

Social cognitive deficits in patients with multiple sclerosis (MS) are associated with higher levels of fatigue, depressive symptoms, and anxiety, new research conducted at the Kessler Foundation has found. Even though the study included only a small group of participants, it represents a step toward better understanding of the underlying…

Multiple sclerosis (MS) is a chronic illness accompanied by various symptoms. Depression is one of the most common. Depression is a shape-shifter and affects one’s life in different ways. The dark hole Imagine one week everything is fine. You’re known for being a social butterfly…

Pear Therapeutics, in collaboration with Novartis, has launched a study evaluating the clinical use of Pear-006, its software-based prescription digital therapeutics (PDT) product for treating depression symptoms in people with multiple sclerosis (MS). PDTs belong to a new class of treatment strategies in healthcare intended to treat diseases,…

Women with multiple sclerosis (MS) are more likely to experience sexual dysfunction and sexual distress than those without the disease, a study reports. According to researchers, the high prevalence of sexual problems among these women may be linked to their age, degree of physical disability, and depression. The…

Retrospective comparison between children with multiple sclerosis (MS) and those with related acute demyelinating syndromes (ADS) highlights the implications of fatigue, depression, and quality of life in these patients. Those are the findings from a study, “Fatigue, depression, and quality of life in children with multiple sclerosis: a…

Study Will Explore Benefits of Tai Chi, Meditation on MS Patients’ Balance I’ve tried yoga to help with my balance and flexibility and found it useful. But tai chi scares me a little — it seems too difficult. Maybe, if the results of this study are very positive, I’ll…

A clinical trial testing a computer program called Deprexis as a home-based therapeutic strategy for multiple sclerosis (MS)-related depression is enrolling participants with all types of MS  at three sites in the U.S. and two in Germany. The U.S. study locations are the Cedars-Sinai Medical Center,…

I am in a funk. It took a lot of mental volleying to admit this. I am preconditioned to synonymize feeling down with weakness. This is simply untrue. I am strong. But I am also having a difficult time managing my disease. Both can be true. In my transparency, I…

Depression and psychological distress symptoms can have a huge effect on the way multiple sclerosis (MS) patients view their well-being, a new study has found. Since depression and psychological distress symptoms can be targeted therapeutically, the study proposes focusing on mental health disorders in MS patients to considerably…