diagnosis

After you get a new diagnosis and are coming to terms with a new way of life, the next part is especially tricky. You have to tell others. “Urgh. I don’t want to tell anyone! Why do I have to?” I’ve had this conversation with myself more than once.

Levels of a protein linked to inflammation and neurodegeneration in multiple sclerosis (MS) — called chitinase 3-like-1 (CHI3L1) — may prove to be a cerebrospinal fluid biomarker of neurologic disability in primary progressive MS (PPMS), a pilot study suggests. Higher CHI3L1 levels at PPMS diagnosis showed a…

The Canadian MS Working Group (CMSWG) — made up of neurologists with the Canadian Network of MS Clinics — has updated its recommendations concerning diagnosis and the use of disease-modifying therapies (DMTs) for multiple sclerosis (MS), according to a press release from the MS Society of Canada.

People with multiple sclerosis (MS) spend a significantly greater number of work days each year on sick leave or disability pay than do the general population — including in the years before they are formally diagnosed, a Swedish study found. Though the number of missed work days rises in…

I have long preached the merits of acceptance. In embracing my MS, I have mitigated much of the accompanying fear. This modus operandi has enabled me to live alongside my disease as opposed to clashing with it. While ideal, it is becoming increasingly difficult to follow my advice. Two…

I saw this question asked in a group somewhere not long ago and it got me thinking. Would I go back to the way I was before my multiple sclerosis diagnosis? No, I wouldn’t.  That may sound strange, I…

More than half of people with brain imaging changes akin to multiple sclerosis (MS) go on to develop the disease within 10 years, a global study of those with radiologically isolated syndrome reported. Progression to MS appears to be more likely in those who are younger, have spinal…

Over the years, I have observed how others deal with multiple sclerosis and its symptoms. This disorder is not one-size-fits-all, and it doesn’t discriminate. Recently, I came across a video of ABC News interviewing actress Selma Blair about her multiple sclerosis diagnosis and management. Although the interview happened over…

Psychosis and cognitive difficulties may be initial symptoms of relapsing‐remitting multiple sclerosis (RRMS), a case report says. “A case report revealing acute onset psychosis and cognitive impairment as primary manifestation in relapsing‐remitting multiple sclerosis” was published in the journal…

Last updated April 25, 2023 In June, the U.K. marks Carers Week, which got me thinking about how a chronic illness diagnosis often affects a patient’s entire family.  Most often, patients are the focus of a diagnosis, and the people around them are almost forgotten. The…

The National Institutes of Health (NIH) awarded a $7.2 million grant to a team led by Cleveland Clinic researchers that will study whether a new biomarker might more accurately diagnose multiple sclerosis (MS). Grant money will support a study in 400 adults suspected of having MS to determine if the…

Symptoms including sleep disorders and pain may precede by as many as five years the onset of the more well-known symptoms of multiple sclerosis (MS), a study suggests. Understanding these first symptoms could aid in an early diagnosis, allowing treatment to begin at initial stages of disease. The…

Diagnostic guidelines for multiple sclerosis (MS) should be amended to first rule out the presence of neuromyelitis optica spectrum disorder (NMOSD), a neurological inflammatory disease that also affects the brain and spinal cord, a study recommends. The study, “Can a Diagnosis of Multiple Sclerosis Be…

Higher blood levels of the neurofilament light chain (NfL) protein at diagnosis are predictive of worse disability over time in people with multiple sclerosis (MS), a large population study from Sweden suggests. The study, “Plasma neurofilament light levels are associated with the risk of disability in…

I hate needles. Being told I’d need to do injections was the worst news ever, second only to my diagnosis of multiple sclerosis.  Sitting in the neurologist’s office with my husband, Paul, was terrifying. I was 22 and newly diagnosed with…

A portable device that can quickly measure electrical activity in the brain and relay it to doctors via a smartphone app, called the Nurochek system, has been cleared by the United States Food and Drug Administration (FDA) for use as a medical device. Its developer, Headsafe, plans to it…

New Nanosensor May Help to Diagnose MS at Early Stages My neurologist likes to say that “brain is time.” The sooner MS is treated the more time you can buy before the brain begins to deteriorate and MS symptoms appear. Being able to diagnose MS sooner means earlier treatment.

A new tiny sensor is able to detect antibodies against myelin, the protective coating of nerve cell axons whose destruction is a hallmark of multiple sclerosis (MS), potentially allowing for a diagnosis in early disease stages, researchers report. It also offers the possibility of distinguishing multiple sclerosis from neuromyelitis optica, a…

Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum post “An Open Letter to a Newly Diagnosed Patient” and this column by John…

“I can’t move my head,” I thought.  It was 5 a.m. on April 1, and the realization of my full bladder prompted my wakening. But I soon realized I had a more significant issue that only became apparent when I tried to get up and couldn’t. What on…

Editor’s note: This week’s column is inspired by the forum topic “7 Strange and Unusual Symptoms of Multiple Sclerosis” from Nov. 8, 2019. Post your concerns, questions, or experiences in the comments below or at the original forum entry. People with MS often share the symptoms that prompted…

A nerve cell protein found in the blood shows potential as a biomarker of neuroinflammation and future neurodegeneration in the early stages of multiple sclerosis (MS), a study reports. The protein, called serum neurofilament light chain (sNfL), is a known marker of injury to axons (nerve…

Using a mix of broad diagnostic terms and more disease-specific ones may help physicians and patients to better communicate symptoms of autoimmune disorders like multiple sclerosis (MS) that are not always obvious or easy to explain, a study reported. The study, “Using autoimmune strategically: Diagnostic lumping, splitting,…

Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topic “Searching for a diagnosis” from May 14, 2018. Did you undergo evoked potential…

CorTechs Labs presented new data indicating that machine learning models based on magnetic resonance imaging (MRI) of the brain may aid in the early diagnosis of multiple sclerosis (MS). Company representatives, joined by other experts, also released updated recommendations for a standardized…

Myeliviz is the name of a new compound approved for a clinical trial in the U.S. that has the potential to make the process of diagnosing multiple sclerosis faster and tracking the disease progression easier. It does this by providing doctors with a better picture of damaged myelin —…

Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Please visit our forum. I love it that Feb. 29 is Rare Disease Day in 2020. Leap day itself is a rarity, a gift…

A way of detecting the density of proteins in the blood, called “magnetic levitation” or MagLev, may aid in more quickly diagnosing chronic diseases, including the particular type of multiple sclerosis suspected in a person, the scientists who developed this method report. Plasma, the liquid component of blood, is composed of…

Myelin is the protective sheath that covers nerve fibers and is damaged in those with multiple sclerosis. Quantifying the degenerative process of myelin would lend perspective to how much and where a patient is progressing. Currently, MRIs are used for diagnostic purposes, but the nuances of progression remain difficult…

The U.S. Food and Drug Administration (FDA) has granted 510(k) clearance for QyScore, a cloud-based imaging software for the automated quantification of key magnetic resonance imaging (MRI) markers of central nervous system (CNS) disease. MRI is an important tool for diagnosing multiple sclerosis and other CNS disorders. By…