More than 3 million doses of Vueway (gadopiclenol), a lower-dose gadolinium contrast MRI agent used to diagnose and monitor conditions such as multiple sclerosis (MS), have been administered at more than 900 customer sites, maker Bracco Diagnostics said. Approved by the U.S. Food and Drug Administration for use in children…
MRI
A new wearable brain-mapping tool could dramatically change how doctors monitor people with multiple sclerosis (MS), making it easier to track disease progression and guide personalized care. Researchers showed the system, OPM-MEG, reliably detects abnormalities in the brain’s electrical activity in MS patients. The portable technology is a major…
A particular finding on an MRI scan, called the central vein sign (CVS), is sufficient to support a multiple sclerosis (MS) diagnosis without the need for an invasive lumbar puncture, a new U.K. study suggests. The presence of six lesions with a CVS, where a vein is found…
Well, it’s that time of year again, and I’m not referring to allergy season or baseball. It’s time for my MRI to evaluate my multiple sclerosis (MS). For the last three years, I was getting an MRI every 18 months. But at my last visit I saw a…
Before I received my relapsing-remitting multiple sclerosis (MS) diagnosis in 2016, I underwent a standard MRI exam, with and without contrast, that scanned my brain, thorax, and cervical spine. I’d never had an MRI before this one. I was vaguely familiar with what the machine looked like, but it’s…
About a year after I was born, my parents decided to get my ears pierced. Little did they know, it would become an obsession of mine years later. But little did I know, my piercings would pose problems when it was MRI time. When I was 13, I continued…
A three month cognitive rehabilitation program, with or without aerobic exercise, increased tissue volume and activity in brain regions linked to cognition among people with progressive forms of multiple sclerosis (MS), clinical trial data suggests. The MRI findings offer potential biological explanations about why cognitive rehabilitation leads to cognitive…
Magnetic resonance imaging (MRI) is used to diagnose and monitor the progression of multiple sclerosis (MS). We patients can expect to have regular MRIs, although the frequency will depend on our age and disease stability. It’s important that we be comfortable during the procedure, as it…
Lumina Imaging has partnered with the Multiple Sclerosis Association of America (MSAA) to provide affordable brain and spinal cord MRI scans to multiple sclerosis (MS) patients. The partnership makes Lumina the preferred provider for the MSAA’s MRI Access Program in northeast Ohio. The program is designed…
An imaging feature called the T1-dark rim, which is visible on standard MRI scans of people with multiple sclerosis (MS), could help to identify paramagnetic rim lesions (PRLs), a study suggests. PRLs are regions of chronic active inflammation that cause ongoing nerve damage. They’re associated with disease activity and…
As those of us with multiple sclerosis (MS) know, every so often a call comes or a letter arrives telling us we have a date with an extraordinary friend: the magnetic resonance imaging (MRI) scanner. For me, it seems that time has arrived again. Just a few days…
Many years ago, I had an MRI scan on my right knee, and it didn’t go well. In fact, panic set in when I first looked at the scanner, as the tube seemed small. After I lay down and the operator started moving the table, I faced a…
About three-quarters of multiple sclerosis (MS) patients given an under-the-skin formulation of cladribine had no disease activity or didn’t receive any additional therapies 4.5 years after starting treatment, a study shows. Cladribine is the active ingredient in the oral therapy Mavenclad and is typically given in two short treatment…
If you have multiple sclerosis (MS), I’m sure you’ve had several MRIs by now. You’ve probably also had one using a contrast agent. The contrast agent is made from a rare earth element called gadolinium. Mixed with other chemical ions, it highlights lesions or areas…
If you have multiple sclerosis (MS), you’ve probably had several MRIs “with” and “without.” The “with” means injecting a contrast agent containing gadolinium into a vein. The agent then travels into the brain, where it “lights up” areas of active inflammation that otherwise would be difficult or impossible…
When I turned 50 in 2013, I blew out the candles, and bam! I was diagnosed with type 2 diabetes. I started seeing an endocrinologist and a neurologist, taking daily diabetic medications, and testing my blood sugar every day. At that point, I was not physically disabled in any…
Disease severity, brain volume loss, and brain lesions are able to predict later cognitive declines in people with relapsing-remitting multiple sclerosis (RRMS), a study in China found. The study, “Clinical and MRI predictors of cognitive decline in patients with relapsing-remitting multiple sclerosis: a 2-year longitudinal study,”…
The National Institute for Health and Care Evidence (NICE) in England has issued a briefing on the use of Icometrix‘s icobrain system to assess disease activity in people with multiple sclerosis (MS) based on MRI scans. The NICE statement was in the form of a medtech innovation briefing, or…
Loss of gray matter in the spinal cord clearly associates with greater disability in people with multiple sclerosis (MS), but determining the extent of its loss is limited by an inability to accurately measure gray matter in all patients, a small study in Spain reported. The true amount of…
Paramagnetic rim lesions, a specific form of inflammatory damage to the brain, are rarely found in people with disorders other than multiple sclerosis (MS), according to a study in adults with suspected MS. Its findings suggest that looking at PRLs could be useful for diagnosing the disease. Brain Renner,…
This year’s Harry Weaver Neuroscience Scholar Award, funded by the National Multiple Sclerosis (MS) Society, has gone to a Yale University researcher who is searching for biomarkers of radiologically isolated syndrome (RIS) in children. RIS occurs when imaging findings on MRI scans are similar to those seen in people…
Women with relapsing-remitting multiple sclerosis (RRMS) have more brain lesions and accelerated brain volume loss (BVL) after pregnancy compared with pre-pregnancy measurements, recent data showed. Brain lesions in the early postpartum period — the first months following childbirth — were associated with a higher risk of worsened disability and relapse…
Tecfidera (dimethyl fumarate) appears to have similar benefits to Gilenya (fingolimod) in preventing relapses and the loss of motor function and cognition in people with multiple sclerosis (MS), a study with real-world data found. The two medications also led to similar findings on MRI scans, including in…
The U.S. Food and Drug Administration (FDA) has approved Abbott’s request to expand the magnetic resonance imaging (MRI) compatibility with its Proclaim XR spinal cord stimulation system with Octrode leads, which is used to manage chronic pain. The decision lifts previous restrictions for Octrode lead tip location and…
Aubagio (teriflunomide) failed to significantly reduce relapses in children with multiple sclerosis (MS), but two years of treatment decreased the number of brain lesions on MRI scans, according to the final results of the Phase 3 TERIKIDS clinical trial. Importantly, the lack of a signficantly lower relapse rate…
A new collaboration between Arterys and Combinostics seeks to bring comprehensive artificial intelligence (AI) imaging solutions to the diagnosis and care of patients with multiple sclerosis (MS) and other neurological diseases. Under the partnership, Arterys will include Combinostics’ AI-powered cNeuro on its medical imaging cloud AI platform…
The number of lesions affecting the cerebellum — a brain region responsible for coordinating voluntary movements and motor skills such as balance, coordination, and posture — predicts manual dexterity getting worse in people with relapsing-remitting multiple sclerosis (RRMS), according to a retrospective analysis. The study, “Cerebellar pathology and…
Among people with nervous system damage indicative of multiple sclerosis (MS), but who don’t yet have the disease — a condition known as radiologically isolated syndrome or RIS — the risk of progressing to full-fledged MS is higher for those who are younger, have spinal cord lesions, and have…
A blood test for serum neurofilament light chain (sNfL) levels, along with radiological findings, can help to detect early cognitive issues in people recently diagnosed with multiple sclerosis (MS), a study suggests. The study “Cortical Thickness and Serum NfL Explain Cognitive Dysfunction in Newly Diagnosed Patients…
Subtle changes in structure in the hippocampus — a region of the brain involved in processing memories — can differentiate between relapsing-remitting and primary progressive multiple sclerosis, according to a new study. The study, “Unraveling the MRI-Based Microstructural Signatures Behind Primary Progressive and Relapsing–Remitting Multiple Sclerosis Phenotypes,”…