After a week of temperatures at 95 degrees or more making it too hot to swim, today was comfortable enough for me to get back into our condo’s pool. The water temperature was perfect and cool enough to keep me refreshed. I had the best workout I’ve had this season:…
Therapy and counseling
Neuronal Circuit Likely Behind Chronic Itch in MS and Other Diseases Identified I often read posts on multiple sclerosis social media groups complaining about chronic itching. This mouse study may have found a reason for that symptom. The researchers hope that finding the cause will eventually lead to a…
Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topic “How Occupational Therapy Is Improving My MS Home Life” from April 15, 2018.
Convelo Therapeutics has announced a collaboration with Genentech, a member of the Roche Group, to work toward the development of new remyelination therapies for multiple sclerosis (MS) and other myelin disorders. “We are excited to be working with Genentech to…
Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topic “How I Manage Stress With MS” from July 10, 2018. Whether physical, psychological, or…
The Consortium of Multiple Sclerosis Centers (CMSC), working with the Foundation of the CMSC (FCMSC) and EMD Serono, launched a new Mental Health Mini-Mentorship Program to help clinicians better understand the psychological and mental health challenges that people with multiple sclerosis (MS) face on a daily…
The Phase 2 clinical trial testing BrainStorm Cell Therapeutic’s investigational NurOwn therapy for progressive multiple sclerosis (MS) has added a third clinical site, the company announced. The trial (NCT03799718) now will enroll patients at the Keck School of Medicine of The University of Southern California (USC), and its academic…
Confession: I Was a Toxic Person
I confess. I was a toxic person. A “toxic” person can possess many different characteristics — some can be more harmful than others. What do you do when you realize you have a toxic attitude? The beginning I never imagined myself becoming a…
NervGen wants to advance the development of NVG-291, its lead investigational therapy for spinal cord damage, as a potential remyelination treatment for multiple sclerosis (MS), the company announced. Following preclinical data showing that NVG-291 promotes myelin repair and regeneration of damaged nerves in animal models of…
Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topic, “How Chiropractic Therapy Can Help Multiple Sclerosis Patients,” from June 1, 2018.
Progressive MS Patients Have Difficulties Perceiving Thoughts, Intentions of Others, Study Reveals
Patients with progressive multiple sclerosis (MS) have difficulties perceiving the thoughts and intentions, but not the emotions, of other individuals, Kessler Foundation researchers have found. Those findings were reported in a study, “Cognitive but Not Affective Theory of Mind Deficits in Progressive MS,” that was published in…
The loss of immune B-cells, and the resulting changes in the profile of immune T-cells, is a major mechanism of action for the beneficial effects seen with ublituximab treatment in multiple sclerosis (MS) patients, a study suggests. B-cells are a type of immune cell best known for producing…
Startup company Oscine Therapeutics has received an investment from Sana Biotechnology to support the research and development of cell-based therapies for a variety of neurological disorders, including multiple sclerosis (MS). This venture is based on work done over the past several decades in the lab of Steve…
The U.S. Food and Drug Administration (FDA) and the European Medicines Agency (EMA) both agreed to review for possible approval ozanimod, Celgene‘s investigational oral therapy for relapsing forms of multiple sclerosis (MS). An FDA decision on the company’s New Drug Application for ozanimod is expected on…
AxoSim Licenses Mini-Brain Technology, Which May Speed Therapy Discovery for Neurological Diseases
AxoSim has acquired exclusive rights to lab-grown brain miniatures, coined “Mini-Brain,” a technology developed at Johns Hopkins University that uses stem cells to create models of the human brain in a dish. This technique may help speed therapy discovery for many neurological diseases, including multiple sclerosis…
Pear Therapeutics, in collaboration with Novartis, has launched a study evaluating the clinical use of Pear-006, its software-based prescription digital therapeutics (PDT) product for treating depression symptoms in people with multiple sclerosis (MS). PDTs belong to a new class of treatment strategies in healthcare intended to treat diseases,…
Infusible disease-modifying treatment — that is, therapies given intravenously — might have greater benefits for younger people with multiple sclerosis (MS) than oral ones, new research suggests. The research was presented at the ongoing American Academy of Neurology (AAN)’s annual meeting (May 4-10) by Brandi Vollmer,…
Former Vice President Joe Biden has been in some hot water recently because of his habit of hugging some of the people he meets. More generally, in today’s society, some of the casual social touching that once went on, particularly in the workplace, has become out of bounds.
A clinical trial testing a computer program called Deprexis as a home-based therapeutic strategy for multiple sclerosis (MS)-related depression is enrolling participants with all types of MS at three sites in the U.S. and two in Germany. The U.S. study locations are the Cedars-Sinai Medical Center,…
If you’re a member of the baby boomer generation, or if you just like the music of the 1960s and ’70s, you probably know Paul Simon’s “50 Ways to Leave Your Lover“: “‘The problem is all inside your head,’ she said to me. ‘The answer is easy…
About 15 disease-modifying therapies (DMTs) are available to treat MS these days. So, choosing which to use can be daunting. I’ve been treated with four DMTs since I was first prescribed Avonex (interferon beta-1a) back in 1996. Each time I’ve switched treatments, my neurologist has suggested a number of…
Sex and intimacy are good for people with multiple sclerosis (MS), just as they are for anyone without the disease. And while fear of talking with a partner about possible sexual challenges created by MS is perfectly normal, there is help available to deal with potential problems. That’s according…
I have always found group settings to be challenging because of my shy and quiet personality. While I do fine talking to people one-on-one, gatherings of three or more can make me squirm. Years ago, the company I worked for held monthly bonding sessions for…
Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topic “New MS Therapy Company to Focus on Rejuvenating Coating…
Social Cognition Issues Linked to Damage in Specific Brain Region in RRMS Patients, Study Shows
Issues with social cognition can occur in relapsing-remitting multiple sclerosis (RRMS) patients even without the presence of cognitive impairment, and are related to damage in a specific brain region known as the amygdala, a study reports. The study, “Social cognition deficits and the role of…
OK, I’ve used a typical tabloid headline to draw you into a column about dealing with lymphedema. Well, the topic is not exactly sexy! Though my calves are now extremely toasty due to being effectively embalmed. Lymphedema has been plaguing me for years now. There seems to be…
Can you use your mind to attack your MS, just as you use things such as medications and physical therapy? Some people who believe in the benefits of mindfulness think you can, at least to some extent. Mindfulness is defined as “the basic human ability to be fully present,…
An altered metabolism and signaling is associated with the ability of a subset of immune T helper 17 (Th17) cells to induce neuroinflammation, according to a new study of mice. The findings may lead to new treatments for multiple sclerosis (MS) and other chronic inflammatory diseases, the scientists said.
Editor’s note: “Need to Know” is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topic “Anxiety and Depression with MS” from April 30.
We live in a turbulent, violent, and hostile society. We wake up every day to news of another mass shooting, Mother Nature causing unstoppable damage, loud protests by politicians or citizens, or an exchange of angry barbs across social media. Bad news…