February 6, 2024 News by Patricia Inacio, PhD Fatigue predicts worse health-related quality of life in RRMS Fatigue is a significant predictor of worse health-related quality of life in adults with relapsing-remitting multiple sclerosis (RRMS), a study reports. High levels of fatigue were significantlyĀ linked with worse physical and mental health, including cognitive impairments, depression, and anxiety. The findings suggest…
December 19, 2022 News by Steve Bryson, PhD Lcn-2 Protein Marks Intestinal Inflammation in MS, Study Shows People with relapsing-remitting multiple sclerosis (RRMS) have elevated levels of the lipocalin 2 (Lcn-2) protein in their stool samples, a marker for intestinal inflammation, compared with healthy controls, a study demonstrated. Among patients, findings also demonstrated those with high fecal Lcn-2 had changes in their gut microbiome, the collection…
March 16, 2022 News by Marisa Wexler, MS Novantrone Lowers Relapses, Eases Disability in Highly Active RRMS Initial treatment with Novantrone (mitoxantrone) can reduce the risk of relapses and worsening disability in people with highly active relapsing-remitting multiple sclerosis (RRMS), according to a 10-year study from France. “Our results support the short-term use of [Novantrone], followed by a maintenance therapy for patients with early highly…
December 29, 2021 News by Yedida Y Bogachkov PhD NHS England and Wales to Offer Ponvory at Low or No Cost for RRMS Note: This story was updated Jan. 12, 2022, to note that Ponvory is approved in the U.K. for people with relapsing forms of MS who have active disease, defined by clinical or imaging features. The National Institute for Health and Care Excellence (NICE) has recommended thatĀ Ponvory (ponesimod)…
October 22, 2021 News by Somi Igbene, PhD Brain Volume, NfL Level Changes May Predict Disability in Relapsing MS A model that considers changes in brain volume and serum neurofilament (sNfL) levels during the early stages of multiple sclerosisĀ may help clinicians to determine an individual’s likely progression with relapsing forms of MS, a study suggests. āWe were able to build reliable, robust models capable of accurate predictions of…
April 5, 2019 Columns by Jamie Hughes The Unplayable Piano What do a broken-down, out-of-tune piano and multiple sclerosis have in common? Well, theyāre both disorderly and confusing, to say the least. But thereās something else ā they have the potential to bring about something positive. I learned this from a podcast called “Hidden Brain,” specifically from an…
July 5, 2018 News by Iqra Mumal, MSc Grey Matter Atrophy Common to All with MS and Follows Ordered Sequence, Study Finds Grey matter atrophy ā its loss ā Ā follows a sequential pattern that expands to involve more regions of the brain over time in all multiple sclerosis (MS) patients, regardless of their disease type, a new study reports. Atrophy progression is also similar betweenĀ relapsing-remitting multiple sclerosisĀ (RRMS) andĀ primary-progressive multiple sclerosisĀ (PPMS)…