white matter

CNM-Au8 preserves white matter in RRMS patients’ brains: Phase 2 trial

Treatment withĀ CNM-Au8, anĀ experimental oral liquid therapy, led to statistically significant improvements in the health of connections between brain regions for people with stable relapsing-remitting multiple sclerosis (RRMS). That’s according to new MRI data from the Phase 2 VISIONARY-MS trial (NCT03536559), which tested CNM-Au8 against a placebo in…

Longer Breastfeeding May Damage Brain By Delaying DMT Use

Having at least one pregnancy may lower disability scores in women with multiple sclerosis (MS), but breastfeeding for longer than six months may worsen damage to the brain, an observational study in patients has found. Findings support the need for careful pregnancy planning, counseling, and treatment management to ensure…

NervGen Brings Advanced Imaging to Planned NVG-291 Trials

A partnership will allowĀ NervGen to use Imeka‘s proprietary biomarker imaging technology to precisely measure changes in the brain and spinal cord in its upcoming clinical trials, including a study ofĀ NVG-291 in people with multiple sclerosis (MS) NervGen plans to initiate Phase 1b/2Ā trials intoĀ its lead candidate for neural…

Brain Changes in Relapsing MS Found to Follow Pattern

Changes in the amount of grey matter in specific regions of the brain appear to occur early in relapsing multiple sclerosis (MS), while structural changes in white matter happen late in disease progression. These were among the findings of a recent study that tracked the sequence of events in…

Need to Know: Does Brain Matter Matter?

Editor’s note: “Need to Knowā€ is a series inspired by common forum questions and comments from readers. Have a comment or question about MS? Visit our forum. This week’s question is inspired by the forum topicĀ “Grey Matter Atrophy in MS Shown to Follow a Pattern” from July…

This Is What Excites Me About Remyelination Therapy Research

RemyelinationĀ therapies are on the horizon as an innovative multiple sclerosis (MS) treatment, according to my neurologist. These therapies have been on my radar the last few years, but to hear my neurologist say they could soon be a reality makes me hopeful of the possibilities. To offer a…

Imbalances in Brain Microbiota May Be Behind Demyelination in MS, Study Says

Alterations in microorganisms in the brains of multiple sclerosis (MS) patients could contribute to underlying disease mechanisms, including demyelination, according to researchers. The study, ā€œBrain microbiota disruption within inflammatory demyelinating lesions in multiple sclerosis,ā€ was published in the journalĀ Scientific Reports. It is widely recognized that the…

MS Drug May Prevent Brain Damage in Premature Babies

Premature infants are known to be at risk of cerebral injury due to oxygen deprivation and later problems with cognitive development, but anĀ immunomodulating drug mostly used in the treatment of multiple sclerosis (MS) may be of help. Researchers in Germany and Switzerland reported that the drug fingolimod (Gilenya)Ā prevented brain…