News

‘Brain Healthy Lifestyle’ May Help Prevent Disability Progression

Leading a healthy cognitive and physically active lifestyle, including having a normal body weight and well-controlled blood pressure, may increase brain reserve ā€” the brain’s ability to adapt after damage ā€” and delay disability progression in multiple sclerosis (MS), according to a new study. The study, ā€œLifestyle factors…

Semi-synthetic Compound Promotes Myelin Repair in MS Mice

A man-made molecule derived from a naturally occurring amino acid was able to promote the repair of the myelin sheathĀ ā€” a fatty coating around nerve fibers that is damaged in multiple sclerosisĀ ā€” in a mouse model of the disease, a new study reports. “These findings suggest that ……

Natalizumab, Tysabri Biosimilar, Up for Approval in Europe

The European Medicines Agency (EMA) has agreed to review a request to approveĀ Polpharma Biologics‘ biosimilar natalizumab for the treatment of multiple sclerosis (MS). This marks the first time the regulatory agency accepted a marketing authorization application for a biosimilar of Tysabri, anĀ approved MS treatment. “The acceptance…

EMBOLD Study of ATA188 in Progressive MS Is Given Go-ahead

An independent committee of experts has recommended that the Phase 2 portion of the EMBOLD clinical trial continue as planned without a sample size adjustment, following an analysis of safety and effectiveness data. The trial is testing Atara Biotherapeutics‘ experimental medication ATA188 in progressive forms of multiple…

Windstream Among Sponsors of US Veterans Wheelchair Games

For the second year, the communications and software company Windstream is supporting the National Veterans Wheelchair Games, touted as the worldā€™s largest annual wheelchair sports event exclusively for military veterans. The event is for all U.S. veterans with a spinal cord injury, amputation, multiple sclerosis (MS), or other…

Smoking Linked to Worse Outcomes in RRMS Patients After 10 Years

Smoking is associated with lower brain volume, more brain lesions, and greater disability and attention deficits among people with relapsing-remitting multiple sclerosis (RRMS) after 10 years,Ā according to a study in Norway. “The findings imply that patients should be advised and offered aid in smoking cessation shortly after diagnosis, to…

Higher COVID-19 Risk Tied to 2 MS Therapies, Even With Vaccination

Fully vaccinated multiple sclerosis (MS) patients who are treated with Ocrevus (ocrelizumab) or Gilenya (fingolimod) have a significantly higher risk of COVID-19 infection than those given other immunosuppressive therapies, according to a study in Italy. Called breakthrough infections, these post-vaccination cases of SARS-CoV-2 ā€” the virus that causes…

Researchers Distinguish Remyelinated Brain Lesions Via MRI

An MRI technique called quantitative susceptibility mapping (QSM) can be used to accurately identify remyelinated brain lesions in people with multiple sclerosis (MS), a research team has discovered. Remyelinated lesions are those in which the myelin sheath ā€” the protective coating around nerve fibers that is progressively lost…

Estriol Plus Copaxone May Protect Against Nerve Damage in RRMS

Taking the pregnancy hormone estriol in combination with Copaxone (glatiramer acetate) significantly reduced the blood levels of neurofilament light chain (NfL) ā€” a marker of nerve damage ā€” in women with relapsing-remitting multiple sclerosis (RRMS), clinical trial data show. These lower NfL levels were significantly associated with a…