News

Medsenic Being Granted US Patent for Arscimed for RRMS

The U.S. Patent and Trademark Office will grant Medsenic a patent covering the use of Arscimed, its investigational formulation of arsenic trioxide, for the treatment of relapsing-remitting multiple sclerosis (RRMS). Once issued, the patent will protect Arscimed’s use for this indication until 2037. This will add to the already…

Innodem, Novartis Team Up on Trial Testing Eye-tracking Technology

Innodem Neurosciences is teaming up with Novartis Canada on a breakthrough clinical trial to evaluate if Innodem’s digital biomarker eye-tracking technology can monitor disease progression in people with multiple sclerosis (MS). The trial will test Innodem’s “easy-to-use, affordable technology,” which works using visible light, with no special infrared…

Australian Council Supports Research Into MS Risk Factors, Falls

Australia’s National Health and Medical Research Council (NHMRC) is giving a total of AU$6.75 million (about $5 million) in grants to advance research into multiple sclerosis (MS), including risk factors for the disease, preventing falls, and harnessing viral-immune system interactions to improve patients’ lives. The three investigator grants,…

Hydroxychloroquine Shows Potential to Treat PPMS in Phase 2 Trial

Treatment with hydroxychloroquine, an anti-malaria medication, appeared to help slow disability progression among people with primary-progressive multiple sclerosis (PPMS) in a small, proof-of-concept clinical trial. Hydroxychloroquine “is a promising treatment candidate for PPMS and should be investigated further in randomized controlled clinical trials,” its researchers wrote. Results of the study…

1 Year of Ocrevus Not Linked to Higher Risk of Brain Infection PML

One year of Ocrevus (ocrelizumab) treatment does not increase the risk for a rare brain infection — called progressive multifocal leukoencephalopathy (PML) — in people with multiple sclerosis (MS), a study suggests. The study, “Risk Assessment of Progressive Multifocal Leukoencephalopathy in Multiple Sclerosis Patients during…

Deep Brain Stimulation May Help with MS-associated Tremors

Deep brain stimulation (DBS) effectively reduces tremors in people with multiple sclerosis (MS), but may lead to worsening symptoms and speech problems, according to a review study. While these findings support the use of DBS for treating this common, disabling MS symptom, larger studies using standardized measures of…

COVID-19 Stalling MS Research Into Rehabilitation, Quality of Life

The COVID-19 pandemic appears to be stalling research into rehabilitation and quality of life (QoL) for people with multiple sclerosis (MS) in many countries worldwide, a new observational study reports. According to the study, many researchers have found it “significantly more” challenging to recruit participants for studies, and most…

CALLIPER Trial for Progressive MS Enrolls First Patient

Immunic Therapeutics has enrolled the first patient in a Phase 2 clinical trial testing its oral therapy candidate IMU-838 for the treatment of progressive multiple sclerosis (MS). The trial, CALLIPER (NCT05054140), is expected to run in parallel to the company’s two identically-designed Phase 3 trials, dubbed…

Ublituximab, Potential Relapsing MS Therapy, Up for FDA Approval

TG Therapeutics  has applied to the U.S. Food and Drug Administration (FDA) for approval of ublituximab, the company’s investigational anti-CD20 monoclonal antibody therapy for relapsing forms of multiple sclerosis (RMS). Its application was based on data from the ULTIMATE 1 (NCT03277261) and ULTIMATE 2 (NCT03277248) Phase…

Oct. 4 Online Conference Offers Latest Insights Into Progressive MS

An upcoming conference focused on progressive multiple sclerosis (MS) will offer the latest insights about the underlying biology of the disease, and treatment and clinical strategies in development. The one-day conference, “Emerging Research & Trial Strategies for Progressive Multiple Sclerosis,” is taking place virtually on Oct. 4,and is…