In this season of thanks and giving, I have realized the beauty of receiving. I have recognized when to ask for help and how to accept assistance graciously. This has not been my strong suit in the past. I am most at ease with myself when I am of service…
symptoms
Aspirin, administered orally at low doses, was sufficient to suppress multiple sclerosis (MS) symptoms in a mouse model of relapsing-remitting MS (RRMS) and chronic MS, a study reports. The clinical benefits of aspirin were linked to an increase in the number of regulatory T-cells, those responsible for shutting…
A potentially life-threatening case of bleeding in the lungs has been reported and attributed to treatment with Lemtrada (alemtuzumab) by a woman with relapsing-remitting multiple sclerosis. Her medical team found diffuse alveolar hemorrhage in this patient — which resolved in about a week without treatment. The scientists advised that clinicians be alert…
I remember the feeling of having a terrible cold or flu before I had multiple sclerosis (MS). The stuffy nose that made breathing nearly impossible. That elusive tickle in the back of my throat combined with a hacking cough. Cold and flu season is a miserable time, and I…
In Real Time
So, “it” started on Monday. I have no idea what I’m dealing with. Is it a urinary tract infection, a relapse, a bird, or a plane? The superhero metaphor is warranted because, just like in “Avengers: Infinity War,” there will be no resolution by the end. Hmm, I’ve…
I’m coming up on the second anniversary of my Lemtrada (alemtuzumab) treatment. My first infusion round was the first week of December 2016. Round 2, delayed by four months, was done last April. So, it’s time to update my Lemtrada journey for you. Lemtrada, in case you’re not…
The U.S. Congress is supporting with $5 million the National Neurological Conditions Surveillance System (NNCSS), an initiative to be launched by the Centers for Disease Control and Prevention (CDC) to help researchers better understand who develops neurological disorders and why. The NNCSS was authorized by Congress as a part…
High Lipid Levels Associated with Increased Disability, Inflammation in RRMS Patients, Study Shows
High levels of certain lipids, or fat, in the blood are linked to increased disability scores and high levels of pro-inflammatory markers in relapsing-remitting multiple sclerosis (RRMS) patients, a small study reports. The study, “Lipoprotein markers associated with disability from multiple sclerosis,” was published in the journal Scientific…
If you are being treated with Gilenya, take note. The U.S. Food and Drug Administration is warning that if you stop using Gilenya (fingolimod), there’s a chance your MS could become worse. The FDA issued a safety alert saying that this only happens rarely, but when it does, the…
Homotaurine, a compound proven safe for humans in long-term clinical trials, has eased autoimmune responses, brain inflammation, and multiple sclerosis-like symptoms in a mouse model of the disease, a study has found. The findings represent proof-of-principle evidence that homotaurine may represent a new potential class…
The U.S. Food and Drug Administration (FDA) has issued a safety alert, warning that people with relapsing multiple sclerosis (MS) who stop using Gilenya (fingolimod) may experience disease worsening beyond that when starting the medicine or while taking it. Reported cases of such increases in MS disability upon stopping treatment are…
Assessing changes in a person’s heart rate can help to predict the degree to which lymphocyte numbers will decrease in relapsing-remitting multiple sclerosis (RRMS) patients using Gilenya (fingolimod), according to a small study. The research, “Fingolimod-induced decrease in heart rate may predict subsequent decreasing degree of…
Women with multiple sclerosis are being diagnosed at younger ages and in greater numbers than men, except for those with primary progressive disease (PPMS), where men 50 or older tend to predominate, a European review study that looked at trends over several decades reports. The study “Age‐dependent variation of female…
I’ve never liked carnival rides (except for roller coasters) because they make me dizzy. Walking sideways, feeling nauseous, and turning green is not my idea of a fun time! So, I go out of my way to avoid anything that can make my head spin. Yet, for some reason,…
MS-specific Lineage of Oligodendrocytes May Provide New Hints on MS Development Our immune system, according to this study, may not be the only thing playing a role in the development of our MS. The same cells that produce the myelin that coats our nerves may also be…
We’ve all been there. That “uh-oh” feeling hits and you know you’ll be in trouble if you can’t find a restroom, fast. You hope the clerk in the store with the “Restrooms for Customers Only” sign will make an exception if you tell her it’s about to run down…
Multiple sclerosis patients of working age who are unemployed or on a reduced work schedule are likely to show considerable cognitive impairment on tests, especially those measuring mental processing speeds, than patients who are more gainfully employed, a review study reports. This link held true even in patients with little…
I have always prided myself on my smarts. I excelled in college, where I realized my love for learning. I enjoy conversing with others, and I make a concerted effort to expand my horizons. I have never shied away from an opportunity to make another’s acquaintance. Be it current…
The cells that produce myelin in the brain and spinal cord, called oligodendrocytes, may play an active role in the onset or progression of multiple sclerosis (MS), according to a study combining data from MS mouse models and the human brain. This discovery supports the…
“The reason you can’t keep your shorts up,” the orthopedist said, “is because you don’t have enough butt anymore.” It was my first visit with this doctor, and I wasn’t quite sure what to expect. While waiting in a small, wood-paneled anteroom next…
Motor Imagery Set to Musical and Verbal Cues Helps Patients with Walking and Fatigue, Study Says
Mentally rehearsing an ease of walking to rhythmic cues — especially musical and verbal — improves walking speed and distance, and lessens feelings of fatigue in people with multiple sclerosis (MS), a study reports. The study, “Effects and mechanisms of differently…
The pro-inflammatory Th17 cells that characterize multiple sclerosis (MS) may also underlie symptoms of obsessive-compulsive disorder (OCD), results of a mouse study show. The study, “Auto-Reactive Th17-Cells Trigger Obsessive-Compulsive-Disorder Like Behavior in Mice With Experimental Autoimmune Encephalomyelitis,” was published in the journal Frontiers in Immunology. “For the first time,…
Venturing into the world can be overwhelming with multiple sclerosis (MS). Crowds and noise can overload my compromised nervous system, and even my home sanctuary can induce stress when kids, animals, and electronics are present. While others simply hear kids playing or dogs barking, sound becomes shockingly…
Exercise Program Based on Ballet Improves Motor Control and Balance in MS Patients, Study Reports It makes sense. Yoga helps multiple sclerosis (MS) symptoms, as do Pilates and simple stretching. So why shouldn’t ballet? After all, it requires similar balance and motor control. This study only involved…
Appropriate control of immune B-cell numbers and activation in the nervous system is key to preventing inflammation in multiple sclerosis (MS), according to a study. These findings also showed that patients with higher levels of a specific B-cell-regulating cell type had less disease activity. The study, “…
A tragic car crash involving a man with MS is a reminder that we all should be just a little bit more careful than the average driver when we get behind the wheel. The accident happened in early October on a street in Eugene, Oregon. As reported by…
Multiple sclerosis (MS) relapses can be challenging for some patients, and better engagement is needed between patients and their healthcare providers, a study focused on patient experiences has found. The study, titled “Relapse prevalence, symptoms, and health care engagement: patient insights from the Multiple Sclerosis in America 2017 survey,”…
Fall is my favorite season. I love the change in temperature, the falling of amber leaves, trading flip-flops for loafers, the din of football games, and the joy of the holiday season. There is so much to enjoy, yet this particular Sunday I am sick. I have acquired the…
Relapse rates in women with multiple sclerosis (MS) decline during pregnancy, as does the use of disease-modifying therapies, before both adjust to pre-pregnancy levels again, a large U.S. study based on real-world data shows. The study, “Relapses and disease-modifying drug treatment in pregnancy and live birth…
The ability to track multiple sclerosis (MS) at any time, gain a more complete picture of each patient’s disease course and a better understanding of MS are among the possible benefits of the FLOODLIGHT app, according to Laura Julian, PhD, principal medical science director at Genentech. The company…