Measuring the response of the pupil to light stimulating the eye is a non-invasive and easy way to assess multiple sclerosis (MS) severity and progression, researchers report. A clinical study found that poor, or dysfunctional, pupil response was associated with longer disease duration and greater disease severity in relapsing-remitting multiple…
symptoms
When I awaken and start each day, I feel like a hygrometer (a humidity-monitoring device). My body is so in tune to any rise in humidity that I can visualize a red line slowly climbing higher and higher. With each rise of the red humidity line, I can feel…
For ambulatory multiple sclerosis patients with mobility problems, perceptions of being at risk of falling are as important as the risk due to their physical condition — and both should be tested when evaluating fall risk in this patient population, a study reports. The study, “The relationship between physiological…
A new way of interpreting inflammatory signals using the vagus nerve — which carries such signals from throughout the body to the brain — has been found, a study reports. This finding raises the possibility of having a kind of “early warning system” for inflammation, a damaging process in such…
I’ve just dived into the misty world of the allergy medication clemastine. My, there’s a lot already written about it on this site. I was prompted by an article I’d saved on Facebook last year. In an idle moment — which have been pretty scarce lately…
Several studies have demonstrated the therapeutic potential of cannabis and its derivate products to manage the symptoms of multiple sclerosis (MS) and other neurodegenerative diseases. But there is still much to be done to enhance their use and accessibility to patients who may benefit from these therapies, according to…
Growing up in a spiritual family, I can remember hearing the words “we are not going to claim it.” These were words of comfort, hope, and support when a catastrophic event was impending. The dictum was to pray, believe in what you pray for, and to “not claim” whatever…
A survey of multiple sclerosis (MS) patients that looked at their sense of social identity based on their family relations — meant to help explain mood disorders like depression and anxiety seen in this population — found a clear link between the strength of family bonds and mood, a U.K. study…
Dear Diary
I never kept a diary. I did sometimes muse about it but reckoned I’d never become famous enough for one to be useful. Well, at least in that I was right. Until the rise of the smartphone, anniversaries and birthdays were flagged by my oldest son, who has the gift…
Learning impairments in multiple sclerosis (MS) are detected differently by the two most commonly used neuropsychological tests, a new study by the Kessler Foundation shows. The research, titled “Comparing the Open Trial – Selective Reminding Test results with the California Learning Verbal Test II in multiple…
Metabolites produced by microbes in the gut can ease inflammation in the central nervous system by limiting the damage done by microglia, an immune cell of the brain, an early study reports. Its scientists suggest this gut-brain axis may open new avenues to treatment. “These findings provide a clear understanding of how…
Infection with lymphocytic choriomeningitis virus triggers expression of a factor called TOX in immune cells strengthening their migration into the brain and promoting damaging effects, including inflammation and tissue destruction. These findings represent a new piece of the puzzle about the mechanism underlying autoimmune diseases like multiple sclerosis (MS).
B-cell alterations in peripheral blood may predict the conversion of clinically isolated syndrome (CIS) to multiple sclerosis (MS), a recent study suggests. Conducted in Turkey, the study, “Peripheral blood memory B cell frequency predicts conversion from clinically isolated syndrome to multiple sclerosis,” was published in…
A potential biomarker — the ratio of antibody proteins in cerebrospinal fluid at the time of diagnosis — was seen to predict which multiple sclerosis patients will progress into full-blow disability some five years after being diagnosed in a new study. If confirmed in larger clinical studies, this biomarker could to…
Crawling to Deadline
It’s 3:15 p.m. U.K. time on Wednesday, May 9, 2018. My deadline for this column is actually 3 p.m. Gone are the days of blaming the dog for eating my homework; it’s only in the last few minutes that I’ve actually been able to move a bit. From 8:30…
Subtle changes in myelin, the protective layer of nerve fibers, may be an early event in multiple sclerosis (MS) prior to the inflammatory reaction, a new University of Calgary study shows. The study, “Biochemically altered myelin triggers autoimmune demyelination,” was published in the journal Proceedings…
As some have said, “Pain is inevitable; suffering is optional.” I believe I am an optimistic, grateful, and spiritual woman. With that said, I must acknowledge that I have an irresolute reaction when I hear that suffering is optional. Suffering is defined as the state of undergoing pain, distress,…
Exposure to fracking chemicals during pregnancy may aggravate multiple sclerosis (MS) severity and induce an earlier start of symptoms, a new study in mice suggests. The study, “Developmental Exposure to a Mixture of 23 Chemicals Associated With Unconventional Oil and Gas Operations Alters the Immune System…
Pairing wearable sensors with a computer program enables effective monitoring of the way multiple sclerosis (MS) patients walk in “real life,” potentially helping clinicians to better evaluate treatments and judge disability, a small U.K. study reports. The research, “Free-living and laboratory gait characteristics in patients with multiple…
At times I find myself speaking of and referencing my life before my MS diagnosis. My thoughts led to the creation of the following epistle. I believe that words are curative and the spirit absorbs what we speak. As you read my letter to multiple sclerosis, remember that you…
When a doctor orders an MRI with contrast, gadolinium is usually the contrasting agent used. Gadolinium is injected into the patient’s vein after the radiologist takes the first round of MRI images. This helps the radiologist receive sharper, more readable images. In the case of multiple sclerosis (MS),…
#AAN2018 – Neurofilament Light Blood Levels Can Help Define Disease Activity in RRMS, Study Shows
Analysis of a potential blood biomarker linked to brain cell damage can help define disease activity in patients with relapsing-remitting multiple sclerosis (RRMS). Results of a study showed that determining blood levels of neurofilament light chain, or NfL, could help in establishing “no evidence of disease activity,” or NEDA, status…
#AAN2018 – Levels of Protein Derived from Brain Cell Damage Can Mirror Severity of MS, Study Finds
Levels of a protein stemming from brain cell damage can mirror the severity and symptoms of multiple sclerosis, an analysis of combined data from three trials showed. Researchers will present this and related findings at the annual meeting of the American Academy of Neurology in Los Angeles, April 21-27. The…
My morning ritual of showering for a fresh start to my day has progressed to a once-a-week occurrence. Like everything else that my multiple sclerosis (MS) affects, less shower time is not by choice. I take sponge baths daily of course, but actual showers are reserved for when I…
Editor’s note: Tamara Sellman continues her series on the “MS alphabet” with this column referencing terms starting with the letters “U” through “Z.” This is the last post in this series. Symptoms of MS Uhthoff’s phenomenon People with MS are often heat-sensitive and experience overheating due to…
The United States and Australia have issued patents on Sonde Health‘s voice-analysis technology for diagnosing and monitoring multiple sclerosis and other diseases that affect speech. Sonde, which has dubbed its invention vocal biomarker technology, said the U.S. patent is 9,936,914 and the Australian one 2014374349. Both patents cover Sonde’s…
A recent pop-up cafe in Dublin allowed customers to experience what it’s like to live with multiple sclerosis (MS) to highlight the urgent need for improved access to care and treatment for MS patients in Ireland. MSunderstood Café gave customers a small taste of the challenges and symptoms MS…
Online training in meditation based on mindfulness can improve the quality of life for multiple sclerosis (MS) patients while easing depression, anxiety, and sleep problems, a study conducted in Italy reports. These findings add to the growing body of evidence that interventions able…
Editor’s note: Tamara Sellman continues her series on the “MS alphabet” with this column referencing terms starting with the letter “T.” Symptoms of MS Tinnitus You may already know this as “ringing in the ears.” But ringing as a descriptor is a bit subjective, as tinnitus…
Editor’s note: Tamara Sellman continues her series on the “MS alphabet” with this column referencing terms starting with the letter “S.” Last in a series of five. Symptoms of MS Spasticity This refers to the muscle stiffness and issues with muscular control and abnormal muscle tone that…
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