Ampyra

Study examines real-world side effects linked to dalfampridine

The most common real-world side effects linked to dalfampridine ā€” sold as Ampyra and with generics available ā€” are similar to those listed on its prescribing label for multiple sclerosis (MS), according to data from a safety surveillance database. Common side effects included urinary tract infection (UTI), dizziness…

Why I’m Giving 3 MS Medications Another Try

Over the many years I’ve lived with multiple sclerosis (MS), I’ve used several medications to treat my MS symptoms. Some have helped, some haven’t, and some worked at first but then lost their efficacy. I recently returned to three of them that I’d stopped using for various reasons.

NICE Still Opposes Adding Fampyra to NHS for England

The National Institute for Health and Care Excellence (NICE) in England is set to again recommend against adding Fampyra (fampridine) to the list of medications available to multiple sclerosis (MS) patients with walking difficulties through the countryā€™s national health service (NHS). The poor cost-effectiveness of Fampyra ā€” sold…

Ampyra Aids More Than Walking in MS, But Side Effects May Be of Concern

Treatment with oralĀ Ampyra (dalfampridine) improves walking ability, finger dexterity, and cognition in people withĀ multiple sclerosis (MS), an analysis of nine randomized clinical trials shows. But the investigators caution the therapy should be taken only under expert medical guidance, due to its higher rate of potential side effects. The…

MS News that Caught My Eye Last Week: Mavenclad and Ocrevus Use Rising in EU, Ampyra Patent Appeal Denied, Exercise and MS Pilot Study

Mavenclad, Ocrevus Use Rising in EU as Injectables and Tysabri Decline, Spherix Reports I’m not surprised at reports that the use of Mavenclad (cladribine) and Ocrevus (ocrelizumab) is increasing in Europe, or that the use of injectable disease-modifying therapies appears to be declining there. Mavenclad and Ocrevus are approved…

Thereā€™s an App (Maybe Too Many) for That!

How many hours do the pharmaceutical companies think we have in our day? I ask because almost all of them have come up with very slick tools to use, particularly mobile apps, to help us improve our daily lives with MS. Not coincidentally, these apps also provide their…

Fighting in Court Over MS Generics

Biogen is a big pharmaceutical company that produces a half-dozen MS drugs. Among them are Tysabri, Avonex and Tecfidera. And Biogen is doing all it can to protect its turf, particularly when it comes to its best seller,Ā Tecfidera. Last month the company filed lawsuits against several…

Ampyra Aided Walking in PPMS and RMS Patients Over Long Term, Neurologist Says in Interview

AmpyraĀ (dalfampridine) shows long-term efficacy in improving walking ability in peopleĀ with multiple sclerosis, according to a study evaluating the treatment’s use in progressive and relapsing MS patients over two years. The study, ā€œMonitoring long-term efficacy of fampridine in gait-impaired patients with multiple sclerosis,ā€ was published in the…

Transcript of Interview on Ampyra Research, MS Walking Ability and Long-Term Use

Multiple Sclerosis News Today interviewedĀ Dr. Linard Filli,ā€Ø an MS researcher at the University Hospital ZurichĀ involved in clinical studies of prolonged release Ampyra (dalfampridine), on walking ability in MS patients,Ā and Dr. Andrew Blight, chief scientific officer at Acorda Therapeutics, the treatment’s developer. Here is a full transcript of that interview.Ā An…

Ampyra Helps MS Patients Not Only Walk Better, But Feel Better Too, Study Reports

Results from a Phase 2 clinical trial showed that treatment with Ampyra (prolonged-release fampridine) brought bothĀ physical and psychological benefits to patients with multiple sclerosis (MS). These findings,Ā fromĀ the MOBILE study (NCT01597297), were published under the title, ā€œProlonged-Release Fampridine Treatment Improved Subject-Reported Impact Of Multiple Sclerosis: Item-Level Analysis Of The…

#ECTRIMS2016 – MS Patients Achieve Sustained Improvements in Mobility with Ampyra

A recent study showed that the clinical benefits offered by Ampyra (fampridine) in improving mobility among multiple sclerosis (MS) patients hasĀ clinical significance. The results were shown in an oral presentation, ā€œSustained clinically meaningful improvements in walking ability with prolonged-release fampridine: results from the placebo-controlled ENHANCE study,ā€ atĀ the European Committee for…