Photos courtesy of Hayley Crowther Day 1 of 31 This is Hayley Crowther’s story: When I look back at the year I got sick, I’d just celebrated my 30th birthday. I was living with my husband and 7-year-old son, had a job I loved and, just four weeks prior…
mobility
I love the car I drive, but I’ve hated going to the dealer to get my car serviced. In the four decades that I’ve lived with MS, my walking has deteriorated to the point where I use a scooter if I have to walk more than 75 feet. If I…
Helius Medical Technologies has submitted its response to the U.S. Food and Drug Administration (FDA)’s request for more information about the company’s application for de novo classification and clearance of its portable neuromodulation stimulator (PoNS) device to help treat walking difficulties in people…
Adults with mild to moderate multiple sclerosis (MS) are being urged to participate in a new clinical trial — STEP for MS — that will assess the impact of two different exercise programs on patients’ mobility, walking abilities, and quality of life. Funded by the Patient-Centered Outcomes Research…
Virtual Reality-based Rehabilitation May Improve Upper Limb Function in MS Patients, Review Finds
Motor rehabilitation using virtual reality (VR) may improve hand and arm function in people with multiple sclerosis (MS), according to a review study. Evidence of its beneficial effect is, however, still preliminary, as most analyzed studies included small patient groups and some failed to show statistically significant improvements in upper…
An upcoming Phase 2 clinical trial, called ChariotMS, will test whether Mavenclad (cladribine) can slow a worsening of hand and arm function in people with progressive multiple sclerosis (MS) and very limited walking abilities. Patients reliant on wheelchairs or aids to walk even short distances generally have…
Overachieving is my jam. Go big or go home. I strive to be the best at whatever it is I do. Currently, I am achieving greatness in my ability to fall. Three falls in three weeks is a new record. The first one happened in the kitchen. Upon feeling myself…
Helius Medical Technologies partnered with Breakthrough Health on a project focused on understanding how people with multiple sclerosis (MS) in the U.S. evaluate the therapies at their disposal in terms of how well they help their ability to walk. The collaboration will take advantage of an MS companion application, called…
Regulatory T-cells (Tregs) — immune cells that normally dampen immune and inflammatory responses by inhibiting the activity of pro-inflammatory immune cells — enabled mice in a model of multiple sclerosis to partly recover from limb and tail paralysis, scientists reported. Tregs can do this by preventing a subtype of…
Longer exposure to disease-modifying therapies (DMTs) may delay disability progression and the time until people with primary progressive multiple sclerosis (PPMS) require the aid of a wheelchair, an Italian registry-based study found. The study also suggests that starting treatment with DMTs — medications that reduce the activity of…
The idea doesn’t seem very appealing to me, but a company is seeking approval from the U.S. Food and Drug Administration (FDA) for a product that might help people with MS walk better by mildly stimulating the tongue. The portable neuromodulation stimulator (PoNS) is a flat…
Helius Medical Technologies has filed an application with the U.S. Food and Drug Administration (FDA) asking for de novo classification and clearance of its portable neuromodulation stimulator (PoNS) device for the treatment of walking deficits in multiple…
Walking abilities decline earlier and faster than arm and hand function in people recently diagnosed with multiple sclerosis (MS), particularly those with progressive MS (MS), a study showed. These findings, which are consistent with those reported in a previous natural history study called NARCOMS, suggest an ascending order of…
Researchers developed a way of using machine learning to identify those cells most important for a given function or task, such as movement, and for evaluating how they respond to potentially restorative treatments. Using Augur, as this method is called, the team was able to identify the neural circuits in…
I’d just gotten out of bed the other morning and was headed to the bathroom using just one cane when I tried to step over a dog toy on the floor. I went down slowly onto the carpet, so it was really no big deal. No harm, no foul, but…
A multimedia smartphone application designed to precisely inform about exercise and track physical activity led primary or secondary progressive multiple sclerosis (MS) patients to be more active — but no more than a comparison patient group given only a…
MS News That Caught My Eye Last Week: Mayzent, Hookworm Therapy, Walking and Falling, ADS-5102
NICE Does Not Favor Adding Mayzent to NHS England for Active SPMS Currently, the only disease-modifying therapy approved for use in the National Health Service is Betaferon (interferon beta-1b). That’s a 20-year-old treatment considered to be one of the least effective of the DMTs. NICE concedes that clinical trials…
Novartis has awarded a total of $300,000 to two tech companies, honoring each for work done to improve the mobility and independence of people living with multiple sclerosis (MS). The top winner of the Novartis Innovation Prize: Assistive Tech for…
People with multiple sclerosis (MS) exert increased caution with their walking pattern and take smaller steps overall, a study shows. These findings could contribute to the development of better walking rehabilitation programs and decrease the risk of falls. The study, “Influence of Multiple Sclerosis on Dynamic…
ERT, which specializes in clinical trial data collection, announced it has acquired APDM Wearable Technologies (APDM), a provider of wearables and digital biomarkers, to improve the accuracy of key efficacy measures used in clinical studies of multiple sclerosis (MS), Parkinson’s, and other movement disorders. A…
So, Where Do I Start?
Ah, it’s not the blank page that all writers fear that I’m worried about. Those days have long left me. Now it’s applying the discipline to stop! When I first started with a professional writing commission, I sat in the office all day with that fear freezing me. (Those were…
Movements that are an act of “learning” motor tasks after lesions appear in the protective myelin sheath of neurons seem to induce both new and existing oligodendrocytes — the cells that make up myelin — to repair those lesions, a study in mice shows. Precisely timed rehabilitation programs and exercise may…
The United States Patent and Trademark Office has issued a patent covering the intellectual rights to MedRhythms’ proprietary audio engine, a core component of the company’s rhythmic sound products designed to improve the walking ability of adult patients with multiple sclerosis (MS) and other neurological disorders. The…
Nimodipine, an approved medication to prevent brain damage caused by hemorrhage, can be used to prevent spasticity following a spinal cord injury, a mouse study shows. In addition to spinal cord injury, nimodipine may be a promising treatment for neurodegenerative disorders such as multiple sclerosis (MS) and…
I knew a urinary tract infection (UTI) had come a visiting again. I’m now attuned to the slightest hint, like that vague burning after weeing. Indeed, it doesn’t have to burn; it could merely be the faintest tinkle — which is rather apt! This time, it went on to further…
After being rejected twice in the last four years, Fampyra (fampridine; marketed as Ampyra in the U.S.) is now being recommended by the Scottish Medicines Consortium (SMC) for use in the country’s National Health System (NHS) to treat walking disabilities in adults with multiple sclerosis (MS). Scotland…
I’ve just been sentenced to at least 18 months in solitary without time off even for good behavior! Pretty harsh. Luckily, I’m match fit. I’ve already previously done nearly a year trapped in my bedroom with only a commode and basin for most of the day. That was tough.
The neurotechnology company Helius Medical Technologies has received authorization from Health Canada to market its portable neuromodulation stimulator (PoNS) device to treat gait deficit in patients with mild-to-moderate multiple sclerosis…
A new test involving a virtual reality simulation was able to detect balance issues in patients with multiple sclerosis (MS), potentially allowing doctors to identify whether a patient is at risk of falling despite having no apparent problems with walking, according to new research. The results of the study,…
An multi-sensor band worn on the arm or leg, called Myo, can capture and relay difficulties with limb movement due to multiple sclerosis (MS) with an accuracy that mirrors gold standard measures of disability, like the Expanded Disability Status Scale (EDSS), a study reports. These findings support the…